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Progress in Medicine In the last several decades, unprecedented advances in science, technology and medical care have greatly improved the lives of many people and have made a considerable contribution to increased human longevity. These advancements have helped to fight against some of the most life threatening diseases as well as improve upon areas that affect our overall health. Cancer New Technology Major Advancements Future Outlook Charitable Organizations Fluid Biopsy Fluid biopsy extracts cancer cells from a simple blood sample. It might be the next big thing in oncology. Embedded, implanted and digestible sensors In many cases, measuring health parameters at home would be a huge addition to cancer care. Measuring body temperature, for example, is a key in monitoring the effects of chemotherapy. Implanted sensors or digital tattoos could monitor every important vital sign, triggering an alarm to both the patient and the caregiver, so interventions can be planned as quickly as possible. Revolutionary progress against some cancers shows what is possible. Five-year survival rates for breast cancer, testicular cancer and some childhood cancers are now over 90 percent. Today, two out of three people live at least five years after a cancer diagnosis, up from roughly one out of two in the 1970s. The nation's cancer death rate has dropped 18 percent since the early 1990s, reversing decades of increases. Cancer care is set to change more dramatically in the next 20 years than it did in the last 50. Advances in health IT, coupled with a deeper understanding of cancer’s molecular drivers, will help oncologists transform cancer research and care. But continued investments in cancer research will be required to translate recent scientific breakthroughs into new treatments that can address remaining gaps. American Cancer Society Cancer Survivor’s Fund CancerCare.org Cancer Research Institute Children’s Cancer Research Fund The Lance Armstrong Foundation Lungevity Foundation St. Jude’s Susan G. Komen For the Cure Vineman Cancer Charities Fund Heart Diabetes iheart The iheart system measures Aortic stiffness, the best indicator of biological health, through the user’s pulse to determine a user’s Internal Age. By making this technology widely available for consumers, iheart provides users with the ability to monitor their heart health on their own schedule and gives them the motivation needed to pursue a healthy lifestyle. Electronic Stent Researchers have created and tested on animals an electronic stent that releases drugs and can provide diagnostic feedback by measuring blood flow. Doctors can activate the device to speed up drug delivery. The stent can also dissolve when it’s no longer needed. Heart disease has been the leading cause of death in the United States since 1921, and stroke has been the third leading cause since 1938 (1); together they account for approximately 40% of all deaths. Since 1950, age-adjusted death rates from cardiovascular disease (CVD) have declined 60%, representing one of the most important public health achievements of the 20th century. Human genetics will aid not only in prediction of disease but also in the identification of patients for whom a specific pharmacologic or device-related treatment is optimal. In this setting, more-specialized drugs for subpopulations will be developed. As imaging techniques become more definitive and criteria are developed for intervention, it will be easier to review diagnostic information in a straightforward manner, allowing clear monitoring and assessment of the needs for intervention and use of procedures. The Heart Foundation The Children’s Heart Foundation The Hope Heart Institute American Heart Association WomenHeart Mended Hearts Jamie’s Heart Lumee This is a single sensor that can continuously monitor a variety of body chemistry stats, including glucose and oxygen levels, heart rate, respiration and more, and securely transmit the data anywhere via a smartphone app. DietSensor This pocket-sized food scanning device and mobile app with coaching feature is the first of its kind to hit the consumer market. It uses SCiO, a molecular sensor that helps you figure out the chemical makeup of your food or drink by analyzing how the molecules interact using light. Type 2 diabetes can be reversible for up to 2 and one half years (30 months) following very acute weight loss. About 40% of participants who lost weight (starting from an average weight of 220 and dropping to 190, or a 15% weight loss) became non-diabetic and remained non-diabetic for a period of 2 ½ years. The highest likelihood of reversing diabetes was in people with relatively short duration of diabetes, and with higher levels of their own insulin. One of the newer types of medication for diabetes, empagliflozin, can result in a 38% reduction in cardiovascular death, 35% reduction in hospitalization for heart failure, and significant reduction in major cardiovascular events by 14%. Closed-loop systems will become largely available for patients diagnosed with type I diabetes. Improvements in the technology of smartphones, watches, and other portable electronic devices will facilitate the online monitoring of blood glucose, thereby improving treatment and the prevention of complications. In the near future, the screening of patients at risk of diabetes will become widely available, regardless of the socio-economic level. American Diabetes Association Diabetes Hands Foundation Children’s Diabetes Foundation Diabetes Research Institute Foundation The Juvenile Diabetes Research Foundation Joslin Diabetes Center


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